The WHO Global Clinical Platform for severe acute hepatitis of unknown aetiology in children
Multiple countries are reporting severe acute cases of hepatitis of unknown aetiology in children, in several regions of the world. WHO has developed this clinical case report form (CRF) to support and facilitate reporting of anonymized, patient-level data of acute hepatitis of unknown aetiology. It is a secure, limited-access, password-protected platform hosted on REDCap.
This form is intended to support standardized data collection in support of the following objectives:
- To understand the clinical characterization of disease, its natural history and severity.
- To understand risk factors for severe disease, including which children may be at highest risk of the disease and severe outcomes.
- To generate hypotheses about disease aetiology.
- To better characterize the scale of this public health threat to guide the public health response and the development of clinical management guidance including approaches to investigations and infection prevention and control interventions.
WHO invites Member States, health facilities and other entities to participate in the global effort to collect anonymized clinical data relating to suspected or confirmed cases of severe acute hepatitis of unknown etiology and contribute data to the WHO Global Clinical Platform.
Options to contribute clinical anonymized
data:
- directly into the electronic WHO Platform;
- sharing established databases; and
- from printed paper CRFs, with data entered in the WHO Platform
thereafter.
Steps to contribute to the platform:
- Create your profile by registering.
- Review the terms of use.
- After a few days, you will receive an email with the login credentials to access the WHO Platform, or, if you are sharing an established database, additional instructions to contribute data.
For any additional questions, please contact: [email protected]
Case report form
Multiple countries are reporting severe acute cases of hepatitis of unknown aetiology in children, in several regions of the world. WHO has developed this...