PrEP Implementation Tool

Overview

WHO has developed this series of modules to support the implementation of PrEP among a range of populations in different settings. 

The tool contains modules for a range of stakeholders to support them in the consideration, planning, introduction and implementation of oral PrEP. The modules can be used on their own or in combination. In addition, there is a module for individuals interested in or already taking PrEP. 

PrEP should not replace or compete with effective and well-established HIV prevention interventions, such as comprehensive condom programming for sex workers and men who have sex with men and harm reduction for people who inject drugs. Many people who could benefit most from PrEP belong to key population groups that may face legal and social barriers to accessing health services. This needs to be considered when developing PrEP services. Although the public health approach underpins the WHO guidance on PrEP, the decision to use PrEP should always be made by the individual concerned.

Summary

WHO Implementation Tool for Pre-Exposure Prophylaxis (PrEP) of HIV Infection

The overview document provides basic information on the PrEP Implementation Tool including background, target audience and scope, guiding principles, summary of modules and annexes.

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(655 kB)

Oral PrEP Tool app

WHO PrEP App

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Tool modules


1. Clinical

PrEP Implementation Tool - Module 1

This module seeks to provide an overview of relevant information for clinicians, including physicians, nurses and clinical officers, who are providing PrEP in clinical settings. It describes important considerations when starting PrEP in an individual and monitoring PrEP use.

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3.42 MB

2. Community educators and advocates

PrEP Implementation Tool - Module 2

For PrEP services to reach populations in an effective and acceptable way, community educators and advocates are needed to increase awareness about PrEP in their communities. This module provides up-to-date information on PrEP that should be considered in community-led activities that aim to increase knowledge about PrEP and generate demand and access.

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5.78 MB

3. Counsellors

PrEP Implementation Tool - Module 3

This module is for staff who counsel people as they consider PrEP or start taking PrEP and support them in addressing issues around coping with side-effects and adherence strategies. Those who counsel PrEP users may be lay, peer or professional counsellors and healthcare workers, including nurses, clinical officers and doctors.

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1.85 MB

4. Leaders

PrEP Implementation Tool - Module 4

This module aims to inform and update leaders and decision-makers about PrEP. It provides information on the benefits and limitations of PrEP so that they can consider how PrEP could be most effectively implemented in their own settings. It also contains a series of frequently asked questions about PrEP, with related answers. 

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3 MB

5. Monitoring and evaluation

PrEP Implementation Tool - Module 5

This module is for people responsible for monitoring PrEP programmes at the national and site levels. It provides information on how to monitor PrEP for safety and effectiveness, suggesting core and additional indicators for site-level, national and global reporting. 

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3.11 MB

 

6. Pharmacists

PrEP Implementation Tool - Module 6

This module is for pharmacists and people working in pharmacies under a pharmacist’s supervision. It provides information on the medicines used in PrEP, including the optimal storage conditions. It also gives suggestions for how pharmacists and pharmacy staff can monitor PrEP adherence and support PrEP users to take their medication regularly. 

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662.12 kB

7. Regulatory officials

This module is for national authorities in charge of authorizing the manufacturing, importation, marketing and /or control of antiretroviral medicines used for HIV prevention. It provides information on the safety and efficacy of PrEP medicines. Module 7 is currently in planning.

8. Site planning

PrEP Implementation Tool - Module 8

This module is for people involved in organizing PrEP services at specific sites. It outlines the steps to be taken in planning a PrEP service and gives suggestions for personnel, infrastructure and commodities that could be considered when implementing PrEP. 

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3.82 MB

9. Strategic planning

PrEP Implementation Tool - Module 9

As WHO recommends offering PrEP to people at substantial HIV risk, this module offers public health guidance for policy-makers on how to prioritize services, in order to reach those who could benefit most from PrEP, and in which settings PrEP services could be most cost-effective. 

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2.21 MB

10. Testing providers

PrEP Implementation Tool - Module 10

This module is for people who are responsible for providing testing services at PrEP sites and associated laboratories. It offers guidance in selecting relevant testing services, including appropriate screening of individuals before PrEP is initiated and monitoring while they are taking PrEP. Information is provided on testing for HIV, creatinine, hepatitis B and C virus, pregnancy and sexually transmitted infections.

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3.82 MB

11. PrEP users

PrEP Implementation Tool - Module 11

This module provides information for people who are interested in taking PrEP to reduce their risk of acquiring HIV and people who are already taking PrEP – to support them in their choice and use of PrEP. This module gives ideas for countries and organizations implementing PrEP to help them develop their own tools.

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3.29 MB

12. Adolescents and young adults

PrEP Implementation Tool - Module 12

This module is for people who are interested in providing PrEP services to older adolescents and young adults who are at substantial risk for HIV. It provides information on: factors that influence HIV susceptibility among young people;nical considerations for safety and continuation on PrEP; ways to improve access and service utilization; and inclusive monitoring approaches to improve the recording and reporting of data on young people.

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4.79 MB

13. Integrating STI services

WHO implementation tool for PrEP-exposure prophylaxis (PrEP) of HIV infection. Module 13. Integrating STI services

This module is intended to complement the other modules in the WHO PrEP implementation tool. It focuses on the integration of STI services for people who may benefit from or use PrEP. The module is divided into two parts: the first focuses on programme managers and other decision-makers, and the second on health care workers. People who use PrEP will also benefit from the module.

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3.3 MB